How Antioxidant-Enriched Multivitamins Help Cystic Fibrosis
Participation in the study required a long list of qualifications
Additional criteria required for participation in the study involved the following:
- Documentation of 1 or more clinical features including: 2 well-characterized mutations in the cystic fibrosis transmembrane conductance regulator gene and/or sweat chloride equal to or above 60 milliequivalent by quantitative pilocarpine iontophoresis test
- Pancreatic insufficiency documented by having a fecal elastase test
- Weight above 30 kg (about 66 lb) at the screening visit
- Ability to tolerate sputum induction with 3% hypertonic saline and to spit/cough up with induction
- Ability to perform repetitive, consistent efforts in pulmonary function testing
- Ability to swallow soft gel capsules
- Clinical stability with no significant changes in the participant’s health status within 2 weeks prior to randomization
- Written informed consent obtained from the participant or the participant’s legal representative