Healthy Living Understanding Brain Fog in Lupus Patients Prev Slide 3 / 9 Next Prev Next The most common manifestations of lupus To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Some of the most common manifestations of lupus challenges with the brain or NPSLE are detailed below: Seizures Strokes Headaches Mood swings Difficulty concentrating Depression Confusion Fatigue Vision problems