Not really
They only hide or mask the pain.
They offer no treatment.

Hi! Medications can help with pain and to reduce inflammation; however, it would be best to make an appointment for further evaluation.

Oral and topical anti-inflammatory medications can help an ankle sprain, but typically the area also requires some immobilization or bracing for a period of time to get the best outcome.

Anti-inflammatory medications can help with injuries, such as sprains. However, you must take an anti-inflammatory dose. The best way to treat an initial injury is to use ice, elevate the affected limb, compress the ankle with a brace or ACE bandage. If the pain and swelling last more than a week, or if you can not bear weight on the affected ankle, seek medical attention ASAP

Medications, such as anti inflammatories can be helpful after an ankle sprain. I recommend you make an appointment with a foot and ankle surgeon (podiatrist) for evaluation, diagnosis and treatment options.