Only with a healthy plan that includes healthy eating. This means a diet consisting of protein and significantly decreasing carbohydrates (sugar, flour, potatoes, etc.). Girls develop 80% of their fat cells by the age of 1, and the other 20% during puberty, so it will take commitment and consistency lifelong. We can't change our genetics, but we can change what we eat. I also suggest following with someone who specializes in helping people lose weight and keep it off. Go online to: https://obesitymedicine.org/find-obesity-treatment/ and find a bariatric physician near you that you are comfortable with and they will help your daughter on her journey. This is a critical time in her life, both physically and emotionally, and her quality of life will depend on the decisions and successes that you make with her now.