• Sertraline dose?

I increased my sertraline dose from 50 to 75 mg about 2 weeks ago but now I've started to feel a lot worse in terms of my mood and not sleeping well. Please give me advice, should I give it more time?

3 Answers

  • Physician Assistant | Medical
  • Fort Lauderdale, FL

You should give it more time and I suggest you take it at bedtime.

  • Pharmaceutical Medicine
  • Lake Charles, LA

Usually, it takes 2 weeks to a month before feeling better.

  • Pharmacist
  • Marion, AR

Hello, did you increase the dose, or did your doctor/prescriber increase your dose to 75mg? It can take from 4 to 6 weeks to see the full benefit from an increase in your dose of an SSRI like sertraline.

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