There are multiple new meds that can be used in combo
Also need to evaluate kidney function
And secondary causes of hypertension
Thanks

Resistant hypertension can be managed with mineralocorticoid receptor antagonists as add on therapy to the other antihypertensive medications. Novel antihypertensives like aldosterone synthase inhibitors can reduce the aldosterone production directly and interventional approaches like renal sympathetic nerve denervation and baroreceptor stimulation for selective patients can help regulate blood pressure in patients with resistant hypertension. Lifestyle modifications and evaluating the causes for secondary hypertension such as cushing syndrome, sleep apnea, renal artery stenosis, pheochromocytoma and hyperaldosteronism is essential to optimize the blood pressure control.

The management of RHYM uses both traditional yams new medicines that are Non Steroidal mimetalocorticoid receptors antagonists, which have been found to be a safe to use in patients that have chronic kidney disease . There is also a dual endothelia receptor antagonist for patients at Fisk for hyperkalemia that has offered blood pressure control. Then there are aldosterone synthase inhibitors but the potassium levels must be watched. The use of an extended dosing of Novel angiotensinogen syntheses inhibitors may help with compliance of medication adherence . Ask your doctor for about these options ..