Interesting question. My guess is that you would not have a problem with acupuncture while taking Eliquis. The needles are very fine and they should not be near any major blood vessels. If there were some bleeding, a little pressure for a few minutes should stop it. A lot of superficial surgeries are being done with patient’s just stopping Eliquis for one or 2 doses (not days) and then restarting if there is no bleeding problem.

I do not think acupuncture is invasive. If the person who does this procedure wants you to stop it then you can skip one dose on the previous day &am on the DOP. Then restart.