Dr. David M Holtzman MD

Narcolepsy refers to a sleep disorder characterized by excessive sleepiness during day time. It is a neurological disorder that affect the normal sleep-wake cycle. People with this condition tend to have sudden episodes of sleep that may affect during any time of the day. This disorder can affect...

What are migraines?Migraines are a condition that countless people live with, and often do not seek treatment for. They are severe headaches that come in episodes lasting around 2 to 72 hours. If you have migraines, you may also experience other symptoms such as vomiting, vision problems (seeing...

On average, caregivers in the United States alone spend approximately 18 billion hours caring for those with Alzheimer's disease every year. Not only that, but these hours are unpaid. It could be a terrible burden, as they often need around-the-clock care to remember simple crucial tasks. For loved...

What is encephalitis?Encephalitis means inflammation of the brain. Fever, headache, and joint pain are often experienced in the early stages of encephalitis. Other severe symptoms may develop over some days or hours. They include personality changes, seizures, disorientation, confusion, or...

New Alzheimer’s research shows declining levels of serotonin—the brain chemical linked to memory—could trigger the start of dementia. The finding from Johns Hopkins University School of Medicine opens the possibility of staying the onset of dementia and Alzheimer’s Disease by preventing the...

Targeting particular enzymes to cure diseases or to relieve symptoms has never been an easy task. Indiscriminate targeting often results in unnecessary potentially toxic effects. For the same reasons, early attempts to target HDAC2 were not successful.Researchers knew that HDAC2 plays a vital role...