Dr. Irene M Ghobrial M.D.
Oncologist | Medical Oncology
Dana Farber Cancer Institute 44 Binney Street Boston MA, 02215About
Dr. Irene Ghobrial is an oncologist practicing in Boston, MA. Dr. Ghobrial specializes in the care and treatment of patients with cancer. As an oncologist, Dr. Ghobrial manages and oversees the treatment of a cancer patient after he or she has been diagnosed with the disease. Oncologists will care for their patients throughout the course of the disease. Types of oncologists include medical oncologists, surgical oncologists, radiation oncologists, gynecologic oncologists, pediatric oncologists and hematologist oncologists.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Hematology- 2004
Internal MedicineAmerican Board of Internal MedicineABIM- 2001
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Renal cell carcinoma with acrometastasis and scalp metastasis.
- Management of thalidomide toxicity.
- Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
- Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
- New frontiers in the treatment of multiple myeloma.
- Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenstrom macroglobulinemia.
- Emerging drugs in multiple myeloma.
- Proteomic analysis of waldenstrom macroglobulinemia.
- Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis.
- Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma.
- Novel therapeutic avenues in myeloma: changing the treatment paradigm.
- The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
- Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment.
- Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia.
- Targeting NF-kappaB in Waldenstrom macroglobulinemia.
Clinical Trials
Awards
- 2005 American Society of Hematology Scholar
Treatments
- Waldenstrom Macroglobulinemia, Multiple Myeloma
Fellowships
- Mayo Clinic, Fellow:Hematology/Oncology 2001
- Mayo Clinic, Graduate Medical Education, Hematology & Oncology 2004
Dr. Irene M Ghobrial M.D.'s Practice location
Irene Ghobrial
Dana Farber Cancer Institute 44 Binney Street -Boston, MA 02215Get Direction
Dana Farber Cancer Institute
44 Binney Street -Boston, MA 02215Get Direction
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