Dr. David Lee Wiest MD
Orthopedist
2301 25th St S Suite A Fargo ND, 58103Rating
5/5
About
Dr. David Wiest is an orthopaedic surgeon practicing in Fargo, ND. Dr. Wiest specializes in the diagnosis, treatment and rehabilitation of injuries, diseases and disorders of the bodys musculoskeletal system. As an orthopaedic surgeon, Dr. Wiest tends to bones, ligaments, muscles, joints, nerves and tendons. Orthopaedic surgeons can specialize in certain areas like the hand, spine, hip, foot and ankle, shoulder and elbow or the knee.
Education and Training
Univ of Mi Med Sch, Ann Arbor Mi 1981
University of Michigan Medical School 1981
Board Certification
Orthopaedic SurgeryAmerican Board of Orthopaedic SurgeryABOS
Provider Details
Expert Publications
Data provided by the National Library of Medicine- ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
- Limiting TCR expression leads to quantitative but not qualitative changes in thymic selection.
- The connecting peptide domain of pT alpha dictates weak association of the pre-T cell receptor with the TCR zeta subunit.
- Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand?
- Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro.
- Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo.
- Identification of a novel pre-TCR isoform in which the accessibility of the TCR beta subunit is determined by occupancy of the 'missing' V domain of pre-T alpha.
- Competitive displacement of pT alpha by TCR-alpha during TCR assembly prevents surface coexpression of pre-TCR and alpha beta TCR.
- On the dynamics of TCR:CD3 complex cell surface expression and downmodulation.
- Branching out to gain control: how the pre-TCR is linked to multiple functions.
- Early growth response transcription factors are required for development of CD4(-)CD8(-) thymocytes to the CD4(+)CD8(+) stage.
- Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells.
- Activation-induced ubiquitination of the T cell antigen receptor.
- Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation.
- Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection.
Treatments
- Pain
Dr. David Lee Wiest MD's Practice location
Practice At 2301 25th St S Suite A
2301 25th St S Suite A -Fargo, ND 58103Get Direction
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Nearby Providers
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Dr. Steven W Lantz MD1720 UNIVERSITY DR S FARGO ND 58103![]()
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Dr. Bruce E Piatt MD1720 UNIVERSITY DR S FARGO ND 58103![]()
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Dr. Christopher S Robertson MD2301 25th St S Fargo ND 58103
Nearest Hospitals
ESSENTIA HEALTH-FARGOl
3000 32ND AVE SOUTH FARGO ND 58104SANFORD MEDICAL CENTER FARGOl
801 BROADWAY NORTH FARGO ND 58122ESSENTIA HEALTH ADAl
201 9TH STREET WEST ADA MN 56510