Setting the Boundary: Celiac Disease and Non-Celiac Gluten Sensitivity

These are the key differences for the two conditions:

Celiac Disease

• Well-defined severe illness
• Autoimmune disease that occurs in reaction to gluten consumption
• Affects small intestine 

Non-celiac gluten sensitivity

• Less-defined and less severe illness
• Not an autoimmune disease but body reacts to gluten when consumed
• Does not affect small intestine